Rat FGF-18 protein

• Catalog Number: orb107721
• Category: Proteins
• Description: Recombinant Rat Fibroblast Growth Factor-18. Rat FGF-18 is encoded by the FGF18 gene in rats. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18-/- mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 also has significant roles in lung development and has an anabolic effect on cartilage formation. Additionally, it has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Rat FGF-18 shares 98% amino acid sequence identity with human.
• Target: FGF-18
• Conjugation: Unconjugated
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, 500mM NaCl
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Protein Sequence: EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLLVETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYSGWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQTELQK PFKYTTVTKRSRRIRPTHPG
• MW: 21.0 kDa
• Tested applications: HPLC, SDS-PAGE
• Biological Origin: E.coli
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Alternative names: Rat Fibroblast Growth Factor-18 protein
• Note: For research use only

SDS-PAGE analysis of Rat FGF-18 protein