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Product Overview
Product Name Rat FGF-18 protein
Catalog Number orb107721
ConjugationUnconjugated
Tested applicationsHPLC, SDS-PAGE
Target FGF-18
Alternative Names
Product Properties
Form/Appearance Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4, 500mM NaCl
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Protein Sequence EENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLLVETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYSGWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQTELQK PFKYTTVTKRSRRIRPTHPG
Purity > 95% by SDS-PAGE and HPLC analyses
MW 21.0 kDa
Biological Origin E.coli
Product Description

Recombinant Rat Fibroblast Growth Factor-18. Rat FGF-18 is encoded by the FGF18 gene in rats. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18-/- mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 also has significant roles in lung development and has an anabolic effect on cartilage formation. Additionally, it has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Rat FGF-18 shares 98% amino acid sequence identity with human.

Validation Images
SDS-PAGE analysis of Rat FGF-18 protein
SDS-PAGE analysis of Rat FGF-18 protein
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