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Polzastobart Biosimilar(Anti-LILRB2 / ILT4 / CD85d Reference Antibody)

Polzastobart Biosimilar(Anti-LILRB2 / ILT4 / CD85d Reference Antibody)

Catalog Number: orb2703966

DispatchUsually dispatched within 5-10 working days
$ 3,370.00
Catalog Numberorb2703966
CategoryAntibodies
DescriptionPolzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor.
ClonalityMonoclonal
CAS Number[2640981-19-5]
Antibody TypeBiosimilar Antibody
ConjugationUnconjugated
TargetPolzastobart Biosimilar(Anti-LILRB2 / ILT4 / CD85d Reference Antibody)
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
NoteFor research use only
Expiration Date12 months from date of receipt.