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Catalog Number | orb348916 |
---|---|
Category | Antibodies |
Description | Rabbit monoclonal antibody to Polysialic acid |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | 735 |
Tested applications | FC, IB, IHC, IP, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG |
Immunogen | Homopolymers of α2,8-linked sialic acid of Escherichia coli K1. |
Concentration | 1 mg/ml |
Purity | Purified |
Conjugation | Unconjugated |
Target | Polysialic acid |
Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
Buffer/Preservatives | PBS with 0.02% Proclin 300. |
Alternative names | PSA; N-CAM; neural cell adhesion molecule; polySA Read more... |
Note | For research use only |
Application notes | Clone 735 was used for immunostaining and immunoprecipitation in an experimental setup involving antigen preparation from PBMC (Peripheral Blood Mononuclear Cells) (Husmann et al., 1989; PMID: 2529126). This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al., 1990). 735 was used for Western blot analysis of PSA-NCAM (Polysialylated Neural Cell Adhesion Molecule) (Charter et al., 2000; PMID: 11030751). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al., 2006). |
Expiration Date | 12 months from date of receipt. |
Bitter-Suermann, D. et al. Monoclonal antibodies to polysialic acid reveal epitope sharing between invasive pathogenic bacteria, differentiating cells and tumor cells Immunol Res, 6, 225-237 (1987)
FC, IHC, IP | |
Human, Mouse, Rat | |
Recombinant | |
Unconjugated |
FC, IB, IHC, IP, WB | |
Human, Mouse, Rat | |
Mouse | |
Monoclonal | |
Unconjugated |
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