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Polysialic acid antibody

Polysialic acid antibody

Catalog Number: orb348916

DispatchUsually dispatched within 5-10 working days
$ 688.00
Catalog Numberorb348916
CategoryAntibodies
DescriptionRabbit monoclonal antibody to Polysialic acid
Species/HostMouse
ClonalityMonoclonal
Clone Number735
Tested applicationsFC, IB, IHC, IP, WB
ReactivityHuman, Mouse, Rat
IsotypeIgG
ImmunogenHomopolymers of α2,8-linked sialic acid of Escherichia coli K1.
Concentration1 mg/ml
PurityPurified
ConjugationUnconjugated
TargetPolysialic acid
StorageStore at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
Buffer/PreservativesPBS with 0.02% Proclin 300.
Alternative namesPSA; N-CAM; neural cell adhesion molecule; polySA
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NoteFor research use only
Application notesClone 735 was used for immunostaining and immunoprecipitation in an experimental setup involving antigen preparation from PBMC (Peripheral Blood Mononuclear Cells) (Husmann et al., 1989; PMID: 2529126). This antibody recognises an unusual postranslational modification on neural cell adhesion molecules important in synaptogenesis, oncogenesis (particularly small-cell lung cancer) and development of organs such as the kidney (studied in rats, Lackie et al., 1990). 735 was used for Western blot analysis of PSA-NCAM (Polysialylated Neural Cell Adhesion Molecule) (Charter et al., 2000; PMID: 11030751). In addition to various studies on human cells, the antibody, has also been used the study the fine-composition of poly-sialic acid composition in mice (Galuska et al., 2006).
Expiration Date12 months from date of receipt.
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