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Catalog Number | orb1730569 |
---|---|
Category | Antibodies |
Description | An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | IHC, WB |
Reactivity | Human, Mouse, Porcine |
Isotype | Rabbit IgG |
Immunogen | A synthesized peptide derived from human Phospho-mTOR (S2448) |
Dilution range | WB: 1/500-1/1000; IHC: 1/50-1/100 |
Conjugation | Unconjugated |
MW | Calculated MW: 289 kDa; Observed MW: 289 kDa |
Entrez | 2475 |
UniProt ID | P42345 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Buffer/Preservatives | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Alternative names | MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/thr Read more... |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
FC, IHC-P | |
Bovine, Canine, Equine, Rabbit, Sheep |
FC | |
Human, Mouse | |
Monoclonal | |
APC |
FC | |
Human, Mouse | |
Monoclonal | |
FITC |
FC | |
Human, Mouse | |
Monoclonal | |
PE |
FC | |
Human, Mouse | |
Monoclonal | |
Unconjugated |
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