OX40 Antibody / CD134

• Catalog Number: orb640139
• Category: Antibodies
• Description: CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4+and CD8+T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th)1 and Th2 cells. CD134 is also involved in the stimulation of T cells, T dependent humoral response and generation of optimal CD4+ T cell responses in vivo and in vitro. CD134 is expressed on activated CD4+ T lymphocytes, and its ligand, CD134L, is found preferentially on activated B cells. Engagement of CD134 with its ligand, CD134L, delivers a strong costimulatory signal to effector T cells.
• Clonality: Monoclonal
• Species/Host: Rat
• Isotype: Rat IgG1, kappa
• Conjugation: Unconjugated
• Reactivity: Mouse
• Immunogen: Purified recombinant mouse OX40 antigen was used as the immunogen for the CD134 antibody.
• UniProt ID: P47741
• Tested applications: FACS, IF
• Dilution range: This antibody does not block binding of OX40L,Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml
• Application notes: Optimal dilution of the antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: OX-86
• Formula: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This CD134 antibody is available for research use only.
• Note: For research use only

SDS-PAGE analysis of purified, BSA-free CD134 antibody (clone OX-86) as confirmation of integrity and purity.