Orexin B Human peptide

• Catalog Number: orb216743
• Category: Proteins
• Description: Orexin B Human peptide
• Form/Appearance: Lyophilized powder
• Purity: > 95%
• Protein Sequence: Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2
• MW: 2899.4
• Application notes: Like orexin A, orexin B is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin B to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor).
• Source: Synthetic
• CAS Number: 205640-91-1
• Formula: C₁₂₃H₂₁₂N₄₄O₃₅S
• Storage: Shipped at 4°C. Store at -20°C for one year.
• Alternative names: Hypocretin-2 (human)
• Note: For research use only