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Catalog Number | orb216743 |
---|---|
Category | Proteins |
Description | Orexin B Human peptide |
CAS Number | 205640-91-1 |
Form/Appearance | Lyophilized powder |
Purity | > 95% |
MW | 2899.4 |
Formula | C123H212N44O35S |
Protein Sequence | Arg-Ser-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Ser-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2 |
Source | Synthetic |
Storage | Shipped at 4°C. Store at -20°C for one year. |
Alternative names | Hypocretin-2 (human) Read more... |
Note | For research use only |
Application notes | Like orexin A, orexin B is a hypothalamic neuropeptide regulating the feeding behavior. Central administration of orexin B to rats stimulated food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX₁ receptor is significantly lower (IC₅₀ = 240 nM) than that of orexin A. Binding affinities for the OX₂ receptor are similar for orexin A and B (IC₅₀ = 38 nM and 36 nM, respectively, for displacement of radiolabeled orexin A bound to the receptor). |
Expiration Date | 12 months from date of receipt. |
IHC | |
Human | |
Mouse | |
Monoclonal | |
Unconjugated |
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