Catalog Number | orb61065 |
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CAS Number | 641571-10-0 |
Application notes | BNL |
Note | For research use only. |
Expiration Date | 12 months from date of receipt. |
Description | Nilotinib (AMN-107, Tasigna) is a Bcr-Abl inhibitor with IC50 less than 30 nM. Nilotinib has entered in a phase IV clinical trial in the treatment of philadelphia chromosome positive and chronic myelogenous leukemia in chronic phase. Nilotinib is a selective inhibitor of native and mutant Bcr-Abl. |