Murine SCF protein

• Catalog Number: orb107800
• Category: Proteins
• Description: C-kit ligand, the recently identified ligand for the kit tyrosine kinase receptor, is mapped to the mouse S1 locus. This pleiotropiccytokine, alternately known as stem cell factor (SCF), mast cell growth factor (MGF) and steel-factor (SLF), plays essential rolesin gametogenesis, melanogenesis and early stages of hematopoiesis. In vitro and in vivo, SCF can stimulate the proliferation ofmature, as well as the proliferation and maturation of immature, mast cells. On purified primitive human and mousehematopoietic precursors, SCF acts in a synergistic manner with various growth factors, such as IL-1, IL-3, IL-6, IL-7, and Epo,to induce myeloid, erythroid and lymphoid lineage colony formation. The finding that SCF is also expressed in the nervoussystem suggests a possible role for SCF in the development of the nervous system.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 97% by SDS-PAGE and HPLC analyses
• Conjugation: Unconjugated
• MW: 18.4 kDa
• Target: SCF
• Protein Sequence: MKEICGNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMVIQLSLSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVLC MEENAPKNIK ESPKRPETRSFTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
• Alternative names: Murine Stem Cell Factor protein
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Murine SCF protein