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Murine FGF-18 protein

Catalog Number: orb107720

DispatchUsually dispatched within 2-3 weeks
$ 1,926.00
Catalog Numberorb107720
CategoryProteins
DescriptionRecombinantMurine Fibroblast Growth Factor-18. Murine FGF-18 is encoded by the FGF18 gene. By phylogenetic analysis and gene location analysis, FGF-18 is divided into FGF-8 subfamily which has three members FGF-8, FGF-17 and FGF-18. Using FGF knockout mice model, the numbers of this subfamily were testified that have crucial roles of in embryo development. FGF-18-/-mice have decreased expression of osteogenic markers and delayed long-bone ossification. FGF-18 has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. In addition, it also has significant roles in lung development and has an anabolic effect on cartilage formation.
Tested applicationsHPLC, SDS-PAGE
Purity> 95 % by SDS-PAGE and HPLC analyses
ConjugationUnconjugated
MW21.0 kDa
TargetFGF-18
Protein SequenceEENVDFRIHV ENQTRARDDV SRKQLRLYQL YSRTSGKHIQ VLGRRISARG EDGDKYAQLLVETDTFGSQV RIKGKETEFY LCMNRKGKLV GKPDGTSKEC VFIEKVLENN YTALMSAKYSGWYVGFTKKG RPRKGPKTRE NQQDVHFMKR YPKGQAELQK PFKYTTVTKRSRRIRPTHPG
StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Buffer/PreservativesLyophilized from a 0.2 m filtered concentrated solution in PBS, pH 7.4, 500 mM NaCl
Alternative namesMurine Fibroblast Growth Factor-18 protein
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NoteFor research use only
Expiration Date6 months from date of receipt.
Murine FGF-18 protein

SDS-PAGE analysis of Murine FGF-18 protein

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