Mouse VEGF R3 / FLT4 Protein

Catalog Number: orb511306

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Catalog Numberorb511306
MW111.5 kDa
TargetVEGF R3
Protein SequenceNP_032055.1
SourceMouse VEGF R3 Protein, Mouse IgG2a Fc Tag (FL4-M5251) is expressed from human 293 cells (HEK293). It contains AA Tyr 25 - Asp 770 (Accession # P35917-1).
Biological originMouse
Buffer/Preservatives50 mM Tris, 100 mM Glycine, pH7.5
Endotoxin0.1 EU per μg
NoteFor research use only.
Expiration Date6 months from date of receipt.
DescriptionVascular endothelial growth factor receptor 3 (VEGF R3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belong to the class III subfamily of receptor tyrosine kinases (RTKs). VEGF R3 mediates lymphangiogenesis in response to VEGF-C and VEGF-D. VEGF R3 is widely expressed in the early embryo but becomes restricted to lymphatic endothelia at later stages of development. It is likely that VEGF R3 may be important for lymph angiogenesis.