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Product Overview
| Product Name | Mouse IL-22 Antagonist protein |
|---|---|
| Catalog Number | orb426584 |
| Reactivity | Mouse |
| Conjugation | Unconjugated |
| Target | IL-22 Antagonist |
Product Properties
| Form/Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. IL-22 Antagonist Mouse is lyophilized from a concentrated (1mg/ml) solution in water containing NaHCO3. |
|---|---|
| Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Note | For research use only. |
| Protein Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Val-Asn. |
| Purity | >98.0% as determined by:(a) Gel filtration chromatography under non-denaturing conditions.(b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. |
| Source | Escherichia Coli. |
| Activity | IL-22 E117A mutant is capable of full inhibition of STAT3 phosphorylation induced by mouse interleukin 22 in HepG cells. Its affinity toward immobilized mIL-22 receptor a1 extracellular domain (mIL-22 Ra1-ECD) or IL-22 binding protein is similar to the non-mutated mouse interleukin 22. Mouse IL-22 antagonist (E117A) has very low agonistic activity in this bioassay. |
Product Description
Recombinant of mouse IL-22 Antagonist protein
Solubility (25°C)
| Solubility (25°C) | It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to other aqueous solutions. |
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