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Mouse IL-22 Antagonist Protein
Catalog Number: orb426584
| Catalog Number | orb426584 |
|---|---|
| Category | Proteins |
| Description | Recombinant of mouse IL-22 Antagonist protein |
| Form/Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Purity | Greater than 98.0% as determined by:(a) Gel filtration chromatography under non-denaturing conditions.(b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. |
| Solubility (25°C) | It is recommended to reconstitute the lyophilized Interleukin -22 in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Protein Sequence | The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Val-Asn |
| Source | Escherichia Coli |
| Biological Activity | IL-22 E117A mutant is capable of full inhibition of STAT3 phosphorylation induced by mouse interleukin 22 in HepG cells. Its affinity toward immobilized mIL-22 receptor a1 extracellular domain (mIL-22 Ra1-ECD) or IL-22 binding protein is similar to the non-mutated mouse interleukin 22. Mouse IL-22 antagonist (E117A) has very low agonistic activity in this bioassay. |
| Storage | Stability: Lyophilized Interleukin-22 Mouse Antagonist although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL22 Antagonist should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles |
| Buffer/Preservatives | IL-22 Antagonist Mouse is lyophilized from a concentrated (1mg/ml) solution in water containing NaHCO3. |
| Alternative names | IL-TIF, TIFa, IL-10-related T-cell-derived-inducib Read more... |
| Note | For research use only |
| Application notes | Cytokines And Growth Factors |
| Expiration Date | 6 months from date of receipt. |
