Accelerate Your Research into Mosquito-Borne Diseases

Millions of deaths are caused by mosquito-borne diseases every year. The diseases below have similar symptoms but dramatically different outcomes. Accelerating research of diagnostic techniques could prevent unnecessary deaths. Biorbyt’s high quality antibodies and antigens are perfect for development of diagnostic assays.

We offer a great range of products to enhance your research into Chikungunya, Yellow Fever, Dengue and Zika. We’ve listed a few of our favourite products below.

Chikungunya

Transmission is caused by a bite from an infected female Aedes aegypti. Seen in over 60 countries within North and South America, Asia, Africa and Europe. Symptoms are similar to other mosquito borne diseases therefore misdiagnosis is common. Headache, rash, fever, severe joint and muscle pain and nausea, usually beginning within 8 days of the bite. More severe symptoms are rare. Serum or plasma testing is needed to detect the virus, its nucleic acid, virus-specific immunoglobulin IgM and antibodies, dependant on stage of illness. No effective treatment is available and a commercially available vaccine is yet to be developed.

Catalog #	Description	Clonality / Source	Applications
orb107972	Chikungunya Virus antibody	Mouse Monoclonal B1413M	ELISA
orb1460	Chikungunya Envelope antibody	Mouse Monoclonal	ELISA, LF
orb1431	Chikungunya Envelope antibody	Mouse Monoclonal	ELISA, LF
orb385638	Chikungunya E1 Wild-type protein	Insect Cells
orb385639	Chikungunya E1 Mutant protein	Insect Cells	Control, EIA, LF, WB

Yellow Fever

An acute haemorrhagic disease caused by an arbovirus transmitted by Aedes and Haemogogus species. Symptoms include: fever, muscle pain, vomiting and fatigue but severe liver and kidney disease may develop. Half of individuals suffering severe symptoms die within 10 days, there is no effective treatment. Preventative measures include an effective live-virus vaccine and insect repellent. Prevalent in Central and South America and Africa, infected mosquitoes cause epidemics among dense populations of unvaccinated individuals. Early detection via blood tests and later stage testing to detect antibodies is possible using ELISA kits.

Catalog #	Description	Clonality / Source	Applications
orb13392	Envelope Glycoprotein Yellow Fever Virus antibody	Rabbit Polyclonal	WB, IHC-P, P-ELISA
orb55880	Yellow Fever NS1 antibody	Mouse Monoclonal	ELISA, LF
orb55885	Yellow Fever NS1 antibody	Mouse Monoclonal	ELISA, LF

Dengue

A dramatic increase in spread places around 50% of the world’s population at risk. Dengue is a potentially lethal, mosquito-borne viral infection; a leading cause of child mortality in some Asian and South American countries. The four known serotypes of the virus are mainly transmitted by the female Aedes aegypti mosquito. With no effective treatment, prevention and control of the disease is dependent upon vector control and fast, effective medical care. Detection is via early serum testing and IgM antibody capture using ELISA kits.

Catalog #	Description	Clonality / Source	Applications
orb107980	Dengue Virus NS1 antibody	Mouse Monoclonal B1426M	ELISA, Purification
orb1646	Dengue Virus Envelope antibody	Mouse Monoclonal	ELISA
orb23621	Dengue Types 1,2,3,4 antibody	Mouse Monoclonal BDI419	ELISA, DOT
orb385645	Dengue Type 1 Antigen protein	Vero Cells	ELISA
orb196425	Drosophila	Insect Cells	ELISA, WB

Zika flavivirus

Zika flavivirus is caused by a bite from the Aedes species. The disease is prevalent in tropical and subtropical regions across the globe with cases recorded in Africa, North and South America, Asia and the Pacific. Symptoms range from headaches, inflammation of eyelids, fever etc. to microcephaly in infants of infected mothers and Guillain-Barré syndrome. RNA NAT testing of serum and urine is possible within two weeks of first symptoms. No effective treatment is available, research is currently focused on a range of neurological disorders.

Catalog #	Description	Clonality / Source	Applications
orb371974	Zika Virus Envelope antibody	Mouse Monoclonal	ELISA, LF
orb348810	Zika virus NS1 Protein	Zika virus NS1	-
orb1405	Zika Virus NS1 antibody	Mouse Monoclonal	ELISA, IF/ICC, Purification
orb333866	Zika Virus Envelope protein	Insect cells (Sf-9)	SDS-PAGE
orb333865	Zika Virus NS1 protein	Insect cells (Sf-9)	ELISA, WB

Matched Pair Antibodies for Mosquito-Borne Diseases

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