Accelerate Your Research into Mosquito-Borne Diseases

Millions of deaths are caused by mosquito-borne diseases every year. The diseases below have similar symptoms but dramatically different outcomes. Accelerating research of diagnostic techniques could prevent unnecessary deaths. Biorbyt’s high quality antibodies and antigens are perfect for development of diagnostic assays.

We offer a great range of products to enhance your research into Chikungunya, Yellow Fever, Dengue and Zika. We’ve listed a few of our favourite products below.

Chikungunya

Chikungunya, Dengue, Zika Virus Signpost

Transmission is caused by a bite from an infected female Aedes aegypti. Seen in over 60 countries within North and South America, Asia, Africa and Europe. Symptoms are similar to other mosquito borne diseases therefore misdiagnosis is common. Headache, rash, fever, severe joint and muscle pain and nausea, usually beginning within 8 days of the bite. More severe symptoms are rare. Serum or plasma testing is needed to detect the virus, its nucleic acid, virus-specific immunoglobulin IgM and antibodies, dependant on stage of illness. No effective treatment is available and a commercially available vaccine is yet to be developed.

Catalogue codeDescriptionClonality / SourceApplications
orb107972 Chikungunya Virus antibody Mouse Monoclonal B1413M ELISA
orb1460 Chikungunya Envelope antibody Mouse Monoclonal ELISA, LF
orb383477 Chikungunya Envelope antibody Mouse Monoclonal ELISA
orb385638 Chikungunya E1 Wild-type protein Insect Cells  
orb55896 Chikungunya E2 protein Insect Cells ELISA, WB, LF

Yellow Fever

An acute haemorrhagic disease caused by an arbovirus transmitted by Aedes and Haemogogus species. Symptoms include: fever, muscle pain, vomiting and fatigue but severe liver and kidney disease may develop. Half of individuals suffering severe symptoms die within 10 days, there is no effective treatment. Preventative measures include an effective live-virus vaccine and insect repellent. Prevalent in Central and South America and Africa, infected mosquitoes cause epidemics among dense populations of unvaccinated individuals. Early detection via blood tests and later stage testing to detect antibodies is possible using ELISA kits.

Mosquito
Catalogue codeDescriptionClonality / SourceApplications
orb13392 Envelope Glycoprotein Yellow Fever Virus antibody Rabbit Polyclonal WB, IHC-P, P-ELISA
orb55880 Yellow Fever NS1 antibody Mouse Monoclonal ELISA, LF
orb55885 Yellow Fever NS1 antibody Mouse Monoclonal ELISA, LF

Dengue

A dramatic increase in spread places around 50% of the world’s population at risk. Dengue is a potentially lethal, mosquito-borne viral infection; a leading cause of child mortality in some Asian and South American countries. The four known serotypes of the virus are mainly transmitted by the female Aedes aegypti mosquito. With no effective treatment, prevention and control of the disease is dependent upon vector control and fast, effective medical care. Detection is via early serum testing and IgM antibody capture using ELISA kits.

Catalogue codeDescriptionClonality / SourceApplications
orb107980 Dengue Virus NS1 antibody Mouse Monoclonal B1426M ELISA, Purification
orb1646 Dengue Virus Envelope antibody Mouse Monoclonal ELISA
orb23621 Dengue Types 1,2,3,4 antibody Mouse Monoclonal BDI419 ELISA, DOT
orb385645 Dengue Type 1 Antigen protein Vero Cells ELISA
orb196425 Drosophila Insect Cells ELISA, WB

Zika flavivirus

Destruction of Zika Virus

Zika flavivirus is caused by a bite from the Aedes species. The disease is prevalent in tropical and subtropical regions across the globe with cases recorded in Africa, North and South America, Asia and the Pacific. Symptoms range from headaches, inflammation of eyelids, fever etc. to microcephaly in infants of infected mothers and Guillain-Barré syndrome. RNA NAT testing of serum and urine is possible within two weeks of first symptoms. No effective treatment is available, research is currently focused on a range of neurological disorders.

Catalogue codeDescriptionClonality / SourceApplications
orb371974 Zika Virus Envelope antibody Mouse Monoclonal ELISA, LF
orb372003 Zika Virus NS1 antibody Goat Polyclonal ELISA
orb1405 Zika Virus NS1 antibody Mouse Monoclonal ELISA, IF/ICC, Purification
orb333866 Zika Virus Envelope protein Insect cells (Sf-9) SDS-PAGE
orb333865 Zika Virus NS1 protein Insect cells (Sf-9) ELISA, WB

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