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Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Methylchloroisothiazolinone/Methylisothiazolinone Mixture

Catalog Number: orb1984928

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$ 130.00
Catalog Numberorb1984928
CategorySmall Molecules
DescriptionMethylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW) is an isothiazolinone preservative that is widely used in cosmetics to inhibit the growth of bacteria, yeasts, and fungi, while potentially causing contact skin sensitization. Methylisothiazolinone activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammation.
Purity98.00%
MW264.75
Biological ActivityMethylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) forS. aureus,P. aeruginosa,A. niger, andC. albicans, respectively.2MCIT/MIT can elicit contact sensitization.3Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products.
CAS Number55965-84-9
FormulaC8H9ClN2O2S2
SMILESO=C1C=CSN1C.O=C1C=C(Cl)SN1C
Storage-20°C
NoteFor research use only