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Methylchloroisothiazolinone/Methylisothiazolinone Mixture
Catalog Number: orb1984928
| Catalog Number | orb1984928 |
|---|---|
| Category | Small Molecules |
| Description | Methylchloroisothiazolinone/Methylisothiazolinone Mixture (Kathon 886MW) is an isothiazolinone preservative that is widely used in cosmetics to inhibit the growth of bacteria, yeasts, and fungi, while potentially causing contact skin sensitization. Methylisothiazolinone activates matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammation. |
| CAS Number | 55965-84-9 |
| Purity | 98.00% |
| MW | 264.75 |
| SMILES | O=C1C=CSN1C.O=C1C=C(Cl)SN1C |
| Formula | C8H9ClN2O2S2 |
| Biological Activity | Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002, 0.00005, and 0.00005% (w/w) forS. aureus,P. aeruginosa,A. niger, andC. albicans, respectively.2MCIT/MIT can elicit contact sensitization.3Formulations containing MCIT/MIT have been used for controlling microbial growth in industrial and household products. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
