LHB Antibody / Luteinizing Hormone beta

SKU: orb2641756

Description

Luteinizing Hormone beta/LHB is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease. [RefSeq]

Research Area

Metabolism Research

Images & Validation

• Tested Applications: IHC-P
• Dilution Range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min RT (1)
• Reactivity: Human
• Application Notes:
  Optimal dilution of the LHB antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: CCGD1
• Immunogen: Recombinant beta sub-unit of human LH was used as the immunogen for the LHB antibody.
• Purification: Protein G affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

IHC testing of FFPE human pituitary with LHB antibody (clone CCGD1).

IHC testing of FFPE human pituitary with LHB antibody (clone CCGD1).

Quick Database Links

UniProt

P01229