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LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

Catalog Number: orb1824137

DispatchUsually dispatched within 5-10 working days
$ 780.00
Catalog Numberorb1824137
CategoryAntibodies
DescriptionLysosome-associated membrane proteins (LAMP) are glycosylated type I membrane proteins that play a role in the biogenesis of the pigment melanin. LAMP-5, also known as C20orf103, is a 280 amino acid protein that belongs to the LAMP family and is mainly found in cytoplasmic vesicles of the neuronal cell body. LAMP-5 is up-regulated upon CpG activation and down-regulated up Toll-like receptor (TLR) ligands.
Species/HostMouse
ClonalityMonoclonal
Clone NumberLAMP5/7642
Tested applicationsIHC-P, WB
ReactivityHuman
IsotypeMouse IgG2, kappa
ImmunogenRecombinant full-length human LAMP5 protein was used as the immunogen for the LAMP5 antibody.
Antibody TypePrimary Antibody
Dilution rangeWestern blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
ConjugationUnconjugated
Formula1 mg/ml in 1X PBS; BSA free, sodium azide free
Hazard InformationThis LAMP5 antibody is available for research use only.
UniProt IDQ9UJQ1
StorageAliquot the LAMP5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
NoteFor research use only
Expiration Date12 months from date of receipt.
LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

Western blot testing of human U937 cell lysate with LAMP5 antibody (clone LAMP5/7642). Predicted molecular weight ~31 kDa, but may be observed at higher molecular weights due to glycosylation.

LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

IHC staining of FFPE human kidney tissue with LAMP5 antibody (clone LAMP5/7642). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.

LAMP5 Antibody / Lysosome-Associated Membrane Glycoprotein 5

SDS-PAGE analysis of purified, BSA-free LAMP5 antibody (clone LAMP5/7642) as confirmation of integrity and purity.