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Product Overview
Product Name KRT10 antibody
Catalog Number orb534717
Species/HostRabbit
ReactivityAnimal, Canine, Human
ConjugationUnconjugated
Tested applicationsFACS, IF, IHC-P
Immunogen Recombinant full-length of human KRT10 protein
Target This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Product Properties
Form/Appearance 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Note For research use only.
Isotype IgG
ClonalityMonoclonal
Purity Purified Ab with BSA and Azide at 200ug/ml
MW 56.5 kDa
Clone ID KRT10/1948R
Uniprot ID P13645
Entrez 3858
Product Description

Rabbit monoclonal antibody to KRT10

Application Notes
Dilution Range FACS: 0.5-1 μg/million cells in 0.1ml , IHC-P: 0.1-0.2 μg/ml for 30 min at RT, IF: 0.5-1 μg/ml
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