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KDM3A antibody

Catalog Number: orb67001

DispatchUsually dispatched within 5-10 working days.
$ 527.00
Catalog Numberorb67001
CategoryAntibodies
DescriptionRabbit polyclonal to KDM3A.Lysine-specific histone demethylase 3A (KDM3A) is a histone demethylase that specificallydemethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. KDM3Apreferentially demethylates mono-and dimethylated H3 'Lys-9' residue, with a preference fordimethylated residue, while it has weak or no activity on trimethylated H3 'Lys-9'. KDM3A is involvedin hormone-dependent transcriptional activation, by participating in recruient to androgen-receptortarget genes, resulting in H3 'Lys-9' demethylation and transcriptional activation. KDM3A has beenimplicated in spermatogenesis by regulating expression of target genes such as PRM1 and P1,which are required for packaging and condensation of sperm chromatin. KDM3A is also involved inobesity resistance through regulation of metabolic genes such as PPARA and UCP1.
Species/HostRabbit
ClonalityPolyclonal
Tested applicationsWB
ReactivityHuman
ImmunogenC-terminal region of human KDM3A
Dilution rangeWB:1:1000-1:3000
PurityAffinity purification
ConjugationUnconjugated
MW147
UniProt IDQ9Y4C1
Storage-20°C
Buffer/Preservatives0.01% NaN3
Alternative namesanti-KDM3A antibody,anti-Lysinespecific demethylas
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NoteFor research use only
Expiration Date12 months from date of receipt.
KDM3A antibody

Western blot analysis of total cell extracts from human Jurkat(Lane) and human T47D(Lane2) using KDM3A antibody

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    ELISA,  IF,  IHC-P,  WB

    Gallus, Mouse

    Human, Rat

    Rabbit

    Polyclonal

    Unconjugated

    0.1 mg, 0.02 mg
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    ICC,  IF,  IHC,  WB

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    Polyclonal

    Unconjugated

    200 μl, 100 μl, 50 μl
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    ELISA,  IHC,  WB

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    Rabbit

    Polyclonal

    Unconjugated

    100 μl
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    ELISA,  IF,  IHC,  IP,  WB

    Human, Mouse

    Rabbit

    Polyclonal

    Unconjugated

    100 μg
  • KDM3A Antibody [orb69345]

    ELISA,  IHC,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μl
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