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TROP2 Antibody / TACSTD2
Catalog Number: orb1824590
| Catalog Number | orb1824590 |
|---|---|
| Category | Antibodies |
| Description | TACSTD2/TROP2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells. |
| Clonality | Recombinant |
| Species/Host | Rabbit |
| Isotype | Rabbit IgG, kappa |
| Conjugation | Unconjugated |
| Reactivity | Human |
| Immunogen | A recombinant partial protein sequence (within amino acids 232-323) from the human protein was used as the immunogen for the TROP2 antibody. |
| UniProt ID | P09758 |
| Tested applications | IHC-P |
| Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT |
| Antibody Type | Primary Antibody |
| Clone Number | TACSTD2/7349R |
| Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Hazard Information | This TROP2 antibody is available for research use only. |
| Note | For research use only |
IHC staining of FFPE human prostate carcinoma tissue with TROP2 antibody (clone TACSTD2/7349R). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
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