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AhR agonist 2

AhR agonist 2

Catalog Number: orb1688793

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Catalog Numberorb1688793
CategorySmall Molecules
DescriptionAhR agonist 2
Purity98.00%
MW353.01
Biological ActivityAhR agonist 2 (Compound 12a) is a highly potent agonist of the aryl hydrocarbon receptor (AhR), exhibiting an EC50 value of 0.03 nM. This compound rapidly induces nuclear enrichment of AhR and initiates transcription of downstream genes, thereby promoting skin barrier repair. AhR agonist 2 shows promising potential for psoriasis research [1].
FormulaC12H7Br2N3
SMILESBrC=1C=CC(=CC1)C=2N=C3C=CC(Br)=CN3N2
Storage-20°C
NoteFor research use only