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Human UBC2 protein

Catalog Number: orb107812

DispatchUsually dispatched within 2-3 weeks
$ 1,955.80
Catalog Numberorb107812
CategoryProteins
DescriptionThis E2 enzyme encodes for the human homolog of the yeast DNA repair gene RAD6, which is induced by DNA damagingagents. UBE2B can conjugate ubiquitin to histone H2A in an E3- independent manner in vitro, and is essential for the multiubiquitinationand degradation of N-end rule substrates. Additionally, UBE2B may have a role in sepsis-induced muscle proteinproteolysis and cancer-induced cachexia.
Tested applicationsHPLC, SDS-PAGE
Purity> 95% by SDS-PAGE and HPLC analyses
ConjugationUnconjugated
MW19.0 kDa
TargetUBC2
Protein SequenceMHHHHHHAMG QLRSMSTPAR RRLMRDFKRL QEDPPVGVSG APSENNIMQWNAVIFGPEGT PFEDGTFKLV IEFSEEYPNK PPTVRFLSKM FHPNVYADGS ICLDILQNRWSPTYDVSSIL TSIQSLLDEP NPNSPANSQA AQLYQENKRE YEKRVSAIVE QSWNDS
StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Buffer/PreservativesLyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
NoteFor research use only
Expiration Date6 months from date of receipt.

SDS-PAGE analysis of Human UBC2 protein