Human UBC2 protein

• Catalog Number: orb107812
• Category: Proteins
• Description: This E2 enzyme encodes for the human homolog of the yeast DNA repair gene RAD6, which is induced by DNA damagingagents. UBE2B can conjugate ubiquitin to histone H2A in an E3- independent manner in vitro, and is essential for the multiubiquitinationand degradation of N-end rule substrates. Additionally, UBE2B may have a role in sepsis-induced muscle proteinproteolysis and cancer-induced cachexia.
• Tested applications: HPLC, SDS-PAGE
• Purity: > 95% by SDS-PAGE and HPLC analyses
• Conjugation: Unconjugated
• MW: 19.0 kDa
• Target: UBC2
• Protein Sequence: MHHHHHHAMG QLRSMSTPAR RRLMRDFKRL QEDPPVGVSG APSENNIMQWNAVIFGPEGT PFEDGTFKLV IEFSEEYPNK PPTVRFLSKM FHPNVYADGS ICLDILQNRWSPTYDVSSIL TSIQSLLDEP NPNSPANSQA AQLYQENKRE YEKRVSAIVE QSWNDS
• Storage: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
• Buffer/Preservatives: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
• Alternative names: Human Ubiquitin Conjugating Enzyme E2 B, His prote
• Note: For research use only
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human UBC2 protein