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Product Overview
Product Name Human TWEAK Receptor protein
Catalog Number orb107810
Tested applicationsHPLC, SDS-PAGE
Target TWEAK Receptor
Alternative Names
Product Properties
Form/Appearance Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Purity > 95% by SDS-PAGE and HPLC analyses.
MW 5.6 kDa
Biological Origin E.coli
Product Description

Human TNF-related weak inducer of apoptosis receptor (TWEAKR) also known as Tumor necrosis factor receptor superfamilymember 12A precursor (gene name TNFRSF12A) or fibroblast growth factor-inducable 14 kD protein, is distantly related to theTNFR family, containing one cysteine-rich domain in the extracellular region and a TNFR-associated factor binding domain butdoes not contain a death domain (DD) cytoplasmic region. It is expressed in the spleen, thymus, peripheral blood lymphocytes,colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the solubleTWEAK. In addition, It plays a role in TWEAK-induced endothelial cell migration, proliferation, and angiogenesis.

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