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Catalog Number | orb107809 |
---|---|
Category | Proteins |
Description | Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumornecrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears highpotential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancercells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients. |
Tested applications | HPLC, SDS-PAGE |
Purity | > 97% by SDS-PAGE and HPLC analyses |
Conjugation | Unconjugated |
MW | 14.8 kDa |
Target | sTRAIL Receptor-2 |
Protein Sequence | ESALITQQDL APQQRAAPQQ KRSSPSEGLC PPGHHISEDG RDCISCKYGQ DYSTHWNDLLFCLRCTRCDS GEVELSPCTT TRNTVCQCEE GTFREEDSPE MCRKCRTGCP RGMVKVGDCTPWSDIECVHK ES |
Storage | Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles. |
Buffer/Preservatives | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
Alternative names | Human Soluble Tumor Necrosis Factor-Related Apopto Read more... |
Note | For research use only |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human sTRAIL Receptor-2 protein
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