Human PVRIG Protein

Catalog Number: orb570296

Catalog Number	orb570296
Category	Proteins
Description	Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.
Reactivity	Human
Tag	C-10×His
Form/Appearance	Powder
Purity	90%
Conjugation	Unconjugated
MW	15.6 kDa
Target	PVRIG
Protein Sequence	NP_076975.2
Source	Human PVRIG, His Tag (orb570296) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # Q6DKI7-1).
Expression System	HEK293
Expression Region	Thr 41 - Asp 171
Endotoxins	1.0 EU per μg
NCBI	NP_076975.2
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	C7orf15,C7orf15MGC138295,CD112R,MGC104322,MGC13829 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.6 kDa. The protein migrates as 20-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

Conjugation:	Unconjugated
Purity:	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 38.2 kDa after removal of the signal peptide.The apparent molecular mass of PVRIG-hFc is approximately 55-70 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 10 μg, 50 μg, 100 μg

Human PVRIG full length protein-synthetic nanodisc [orb1743230]
MW:
The human full length PVRIG protein has a MW of 34.3 kDa
Source:
Mammalian
Sizes Available: 10 μg, 50 μg, 100 μg
PVRIG siRNA (Human) [orb1855987]
Applications:
RNA-I
Sizes Available: 30 nmol, 15 nmol
Cynomolgus PVRIG Protein [orb570295]
Conjugation:
Unconjugated
Purity:
95%
MW:
40.1 kDa
Source:
Cynomolgus PVRIG, Fc Tag (orb570295) is expressed from human 293 cells (HEK293). It contains AA Thr 41 - Asp 171 (Accession # A0A2K5WVV8-1).
Sizes Available: 100 μg, 1 mg

Purity:	Greater than 85% as determined by SDS-PAGE.
MW:	50.3 kDa
Source:	in vitro E.coli expression system

MW:	The human full length PVRIG protein has a MW of 34.3 kDa
Source:	Mammalian