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Human CD59 Protein

Human CD59 Protein

Catalog Number: orb668873

DispatchUsually dispatched within 5-10 working days
$ 3,216.00
Catalog Numberorb668873
CategoryProteins
DescriptionCD59, also known as membrane attack complex inhibition factor (MACIF), Protectin, 1F5 antigen, HRF-20 and MIRL. CD59 has been identified as a glycosylphosphatidylinositol-anchored membrane protein that acts as an inhibitor of the formation of the membrane attack complex to regulate complement activation. Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
ReactivityHuman
TagC-10×His
Form/AppearancePowder
Purity95%
ConjugationUnconjugated
MW10.8 kDa
TargetCD59
Protein SequenceLeu 26 - Asn 102
SourceHuman CD59, His Tag (orb668873) is expressed from human 293 cells (HEK293). It contains AA Leu 26 - Asn 102 (Accession # P13987-1).
Expression SystemHEK293
Expression RegionLeu 26 - Asn 102
Endotoxins1.0 EU per μg
Storage-20℃
Buffer/PreservativesPBS, pH7.4
Alternative namesCD59,16.3A5,1F5,EJ16,EJ30,EL32,FLJ38134,FLJ92039,G
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NoteFor research use only
Application notesThis protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.8 kDa. The protein migrates as 15-18 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date6 months from date of receipt.
  • CD59 antibody [orb388925]

    FC,  Functional Studies,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    100 μg, 20 μg
  • Human CD59 ELISA Kit [orb776971]

    Human

    12.5-800 pg/mL

    5.5 pg/mL

    48 Test, 96 Test, 24 t
  • Human CD59 ELISA Kit [orb563505]

    Human

    31.25-2000pg/ml

    18.75pg/ml

    96 Test
  • Rat Cd59 ELISA Kit [orb567112]

    Rat

    0.156-10ng/ml

    0.094ng/ml

    96 Test
  • Human CD59 protein [orb245784]

    Greater than 90% as determined by SDS-PAGE.

    11 kDa

    Yeast

    20 μg, 100 μg, 1 mg
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