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Human CD47 Protein

Catalog Number: orb257295

DispatchUsually dispatched within 5-10 working days
$ 3,216.00
Catalog Numberorb257295
CategoryProteins
DescriptionLeukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
ReactivityHuman
TagC-Fc
Form/AppearancePowder
Purity95%
ConjugationUnconjugated
MW40.4 kDa
TargetCD47
Protein SequenceNP_942088
SourceHuman CD47, Fc Tag (orb257295) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Pro 139 (Accession # NP_942088).
Expression SystemHEK293
Expression RegionGln 19 - Pro 139
Endotoxins1.0 EU per μg
NCBINP_942088
Storage-20℃
Buffer/Preservatives50 mM Tris, 100 mM Glycine, pH7.5
Alternative namesCD47,MER6,IAP,OA3
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NoteFor research use only
Application notesThis protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.4 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date6 months from date of receipt.
Human CD47 Protein

SDS-PAGE analysis of Human CD47 protein

Human CD47 Protein

Line graph illustrates about the sensitivity range of Human CD47 protein using different concentrations

  • Human SIRP alpha / CD172a Protein [orb257842]

    Unconjugated

    95%

    38.5 kDa

    Human SIRP alpha, His Tag (orb257842) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Arg 370 (Accession # NP_001035111).

    1 mg, 100 μg
  • Human SIRP alpha / CD172a Protein [orb257843]

    Unconjugated

    95%

    63.9 kDa

    Human SIRP alpha, Fc Tag (orb257843) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Arg 370 (Accession # NP_001035111).

    1 mg, 100 μg
  • Human SIRP alpha / CD172a Protein [orb257844]

    Unconjugated

    95%

    63.0 kDa

    Human SIRP alpha, Mouse IgG1 Fc Tag (orb257844) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Arg 370 (Accession # NP_001035111).

    1 mg, 100 μg
  • Human CD47 Protein [orb257293]

    Unconjugated

    95%

    15.6 kDa

    Human CD47, His Tag (orb257293) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Pro 139 (Accession # NP_942088).

    1 mg, 100 μg
  • CD172a Antibody (FITC) [orb1570907]

    FC

    Human

    Mouse

    Monoclonal

    FITC

    100 tests
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