| Category | Proteins |
|---|---|
| Catalog Number | orb511272 |
| Reactivity | Human |
| Conjugation | Unconjugated |
| MW | 46.5 kDa |
| Target | CD30 ligand |
| Application notes | This protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
| Protein Sequence | NP_001235.1 |
| Tag | N-mFc(mIgG2a) |
| Source | Human CD30 Ligand Protein, Mouse IgG2a Fc Tag (orb511272) is expressed from human 293 cells (HEK293). It contains AA Gln 63 - Asp 234 (Accession # P32971-1). |
| Biological origin | Human |
| Storage | -20℃ |
| Purity | 95% |
| Form/Appearance | Powder |
| Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
| Endotoxin | 0.1 EU per μg |
| Note | For research use only. |
| Expiration Date | 6 months from date of receipt. |
| Description | CD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated. |
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