Human CD30 Ligand / TNFSF8 Protein

Catalog Number: orb511272

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Catalog Numberorb511272
MW46.5 kDa
TargetCD30 ligand
Application notesThis protein carries a mouse IgG2a Fc tag at the N-terminus. The protein has a calculated MW of 46.5 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Protein SequenceNP_001235.1
SourceHuman CD30 Ligand Protein, Mouse IgG2a Fc Tag (orb511272) is expressed from human 293 cells (HEK293). It contains AA Gln 63 - Asp 234 (Accession # P32971-1).
Biological originHuman
Buffer/PreservativesTris with Glycine, Arginine and NaCl, pH7.5
Endotoxin0.1 EU per μg
NoteFor research use only.
Expiration Date6 months from date of receipt.
DescriptionCD30 ligand (CD30L) and CD30 are interacting cellsurface glycoproteins that are members of the tumour necrosis factor (TNF) and tumour necrosis factor receptor (TNFR) superfamilies. In humans, CD30L is expressed at high levels on activated T cells. There is conflicting evidence with regard to cell surface expression of CD30L on primary human B cells. An initial report of constitutive CD30L expression on peripheral blood B cells33 has not been substantiated.