| Category | Proteins |
|---|---|
| Catalog Number | orb511316 |
| Reactivity | Human |
| Conjugation | Unconjugated |
| MW | 46.2 kDa |
| Target | CD27 |
| Protein Sequence | NP_001233.1 |
| Tag | C-mFc(mIgG2a) |
| Source | Human CD27 Protein, Mouse IgG2a Fc Tag (CD7-H5257) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # P26842-1). |
| Biological origin | Human |
| Storage | -20℃ |
| Purity | 95% |
| Form/Appearance | Powder |
| Buffer/Preservatives | 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 |
| Endotoxin | 0.1 EU per μg |
| Note | For research use only. |
| Expiration Date | 6 months from date of receipt. |
| Description | CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3. |
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