Category | Proteins |
---|---|
Catalog Number | orb511324 |
Reactivity | Human |
Conjugation | Unconjugated |
MW | 64.1 kDa |
Target | ANGPTL7 |
Protein Sequence | NP_066969.1 |
Tag | C-mFc(mIgG2a) |
Source | Human ANGPTL7, Mouse IgG2a Fc Tag (AN7-H5252) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Pro 346 (Accession # O43827-1). |
Biological origin | Human |
Storage | -20℃ |
Purity | 90% |
Form/Appearance | Powder |
Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
Endotoxin | 1.0 EU per μg |
Note | For research use only. |
Expiration Date | 6 months from date of receipt. |
Description | Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells. |