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Product Overview
Product Name GW2580, Free Base
Catalog Number orb61037
ConjugationUnconjugated
Tested applicationsFACS
Target GW2580, Free Base
Alternative Names
Product Properties
Form/Appearance White powder
Storage Store at -20°C for two year solid and six months at -80°C in DMSO
Note For research use only.
Purity

>99% pure

Formula C20H22N4O3
MW 366.41 g/mol
CAS Number [870483-87-7]
Chemical Name

5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine

PubChem CID CID 11617559
Product Description

GW2580, a cFMSkinase inhibitor, inhibits colony-stimulating factor (CSF)-1-induced monocyte growth and bone degradation and CSF-1 signaling through cFMS kinase

Application Notes
Application Notes Add Tween 80 to your media (final concentration: 0.1% w/v), the surfactant Tween 80 can help GW2580 to dissolve in water media.
Solubility (25°C)
In vitro
DMSO131mM
Alcohol<1mM
Water<1mM
Validation Images
GW2580, Free Base
GW2580, Free Base
GW2580, Free Base: CSF-1 Receptor Inhibitor, GW-2580, GW632580X
GW2580, Free Base: CSF-1 Receptor Inhibitor, GW-2580, GW632580X
Chemical Structure of GW2580, Free Base
Chemical Structure of GW2580, Free Base
GW2580, Free Base
GW2580, Free Base
Additional Documents
References

Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

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