Gitoxin

SKU: orb1682497

Description

Gitoxin is a cardenolide metabolite of digitoxin that acts as a Na⁺/K⁺-ATPase inhibitor. It exhibits antiarrhythmic properties and inhibits human erythrocyte isoenzymes at micromolar concentrations. This small molecule is used in cardiovascular research to study ion transport mechanisms in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 4562-36-1
• MW: 780.94
• Formula: C₄₁H₆₄O₁₄
• SMILES: O[C@@]12[C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@@H](O[C@H]5C[C@H](O)[C@H](O[C@H]6C[C@H](O)[C@H](O[C@H]7C[C@H](O)[C@H](O)[C@@H](C)O7)[C@@H](C)O6)[C@@H](C)O5)CC4)[H])(CC[C@]1(C)[C@H]([C@@H](O)C2)C8=CC(=O)OC8)[H])[H]
• Target: ATPase,Others,Drug Metabolite
• Solubility: Ethanol:6 mg/mL (7.68 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gitoxin

Compound Identifiers

PubChem CID

91540