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Fluticasone
Catalog Number: orb422378
| Catalog Number | orb422378 |
|---|---|
| Category | Small Molecules |
| Description | Fluticasone is a synthetic glucocorticoid which is used in some countries to treat nasal symptoms. |
| MW | 444.507596254349 |
| CAS Number | 90566-53-3 |
| Formula | C22H27F3O4S |
| SMILES | C[C@@]12[C@@](O)(C(=O)SCF)[C@H](C)C[C@H]1[C@@H]1C[C@H](F)C3=CC(C=C[C@]3(C)[C@]1([C@H](C2)O)F)=O |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Fluticasone propionate [orb1223965]
>98%(HPLC)
80474-14-2
500.6
C25H31F3O5S
1 g, 500 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mgFluticasone 17β-Carboxylic Acid [orb1694107]
28416-82-2
396.42
C21H26F2O5
250 mg, 500 mg, 100 mg, 50 mgFluticasone (propionate) [orb1310855]
99.65%
80474-14-2
500.57
C25H31F3O5S
200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 500 mg, 1 ml x 10 mM (in DMSO)Fluticasone furoate [orb1306375]
99.58%
397864-44-7
538.58
C27H29F3O6S
500 mg, 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 1 ml x 10 mM (in DMSO)
For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:
Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.Note:
- For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
- We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.
