FBW7 antibody

• Catalog Number: orb67185
• Category: Antibodies
• Description: Rabbit polyclonal to FBW7.F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination andsubsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds tophosphorylated target proteins. FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1released notch intracellular domain (NICD), and probably PSEN1.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: WB
• Reactivity: Human
• Immunogen: N-terminal region of human DDB1
• Dilution range: WB:1:1000-1:3000
• Purity: Affinity purification
• Conjugation: Unconjugated
• MW: 80
• UniProt ID: Q969H0
• Storage: -20°C
• Buffer/Preservatives: 0.01% NaN3
• Alternative names: anti-FBW7 antibody,anti-Fbox antibody,anti-WD repe
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Western blot analysis of total cell extracts from human Hela(Lane1) and human T47D(Lane2) using FBW7 antibody