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Elastin Antibody

Elastin Antibody

Catalog Number: orb606578

DispatchUsually dispatched within 5-10 working days
$ 764.00
Catalog Numberorb606578
CategoryAntibodies
DescriptionElastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Species/HostMouse
ClonalityMonoclonal
Clone NumberELN/1981
Tested applicationsELISA, IHC-P
ReactivityHuman
IsotypeMouse IgG1, kappa
ImmunogenRecombinant full length human protein was used as the immunogen for the Elastin antibody.
Dilution rangeELISA (order BSA/sodium azide-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
PurityProtein G affinity chromatography
ConjugationUnconjugated
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Hazard InformationThis Elastin antibody is available for research use only.
UniProt IDP15502
StorageStore the Elastin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
NoteFor research use only
Application notesTitering of the Elastin antibody may be required for optimal performance.
Expiration Date12 months from date of receipt.
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