EGFR-IN-86

EGFR-IN-86 (compound 4i) is a potent and selective EGFR inhibitor with an IC50 of 1.5 nM. It exhibits anti-glioblastoma activity in U87 cell models by triggering apoptotic cell death and inducing G2/M phase cell cycle arrest, supporting its use in oncology research for investigating EGFR-driven cancers.