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Catalog Number | orb1309719 |
---|---|
Category | Small Molecules |
Description | EG00229 |
Purity | 97.20% |
MW | 611.6 |
Biological Activity | EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2. |
CAS Number | [1210945-69-9] |
Formula | C19H20F3N7O7S3 |
SMILES | OC(=O)C(F)(F)F.NC(=N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O |
Storage | -20°C |
Note | For research use only |