CNB-001

SKU: orb2566613

Description

CNB-001 is a research compound that potently inhibits 5-lipoxygenase (5-LOX), reducing its expression and enhancing proteasome activity. In Alzheimer's disease models, it modulates eIF2α phosphorylation, HSP90, and ATF4 to limit Aβ and aggregated proteins, while preserving synaptic markers and improving memory, making it valuable for neurodegenerative disease research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1019110-87-2
• MW: 440.49
• Formula: C₂₇H₂₄N₂O₄
• SMILES: C(=C/C1=CC(OC)=C(O)C=C1)\C=2N(N=C(/C=C/C3=CC(OC)=C(O)C=C3)C2)C4=CC=CC=C4
• Target: Lipoxygenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135440402