Cephalexin monohydrate

SKU: orb1705859

Description

Cephalexin monohydrate is a semi-synthetic, first-generation cephalosporin antibiotic for research use. It acts by inhibiting penicillin-binding proteins (PBPs) to block bacterial cell wall synthesis. This compound is widely applied in in vitro antimicrobial studies and in vivo models of bacterial infection.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 23325-78-2
• MW: 365.40
• Purity: 99.11%
• Formula: C₁₆H₁₉N₃O₅S
• SMILES: O=C1N2[C@@]([C@@H]1NC([C@H](N)C3=CC=CC=C3)=O)(SCC(C)=C2C(O)=O)[H].O
• Target: Antibiotic,Antibacterial
• Solubility: H2O:1 mg/mL (2.74 mM);DMSO:5 mg/mL (13.68 mM)

Bioactivity

• In Vivo:
  In male Swiss-Webster mice infected with bacteria, cephalexin monohydrate (0-50 mg/kg; oral administration; for 3.5 hours) exhibited antibacterial activity against Streptococcus pyogenes, Streptococcus pneumoniae, Staphylococcus aureus, and several gram-negative species.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cephacillin hydrate, Cephalexin, Cephalexin hydrate, Cefalexin hydrate, Cefalival, Cefibacter, Antibiotic

Compound Identifiers

PubChem CID

62921