CD3 reagents

CD3 Reagents

CD3: Cluster of differentiation 3

This T-cell receptor helps to activate both cytotoxic T-cells (CD8+ naive T-cells) and T helper cells (CD4+ naive T-cells).  Present as a protein complex, it comprises 4 distinct chains.  In mammals, this complex contains a gamma, delta and two epsilon chains.

The CD3γ, CD3δ and CD3ε chains are highly related cell-surface proteins and contain a single extracellular immunoglobulin domain.

CD3 antigen can be found bound to the membranes of all mature T-cells and in virtually no other cell type.  This high specificity, combined with its presence at all stages of T-cell development makes it a useful T-cell marker for IHC tissue sections.  The antigen is also present in almost all T-cell lymphomas and leukaemias, allowing their differentiation from similar B-cell and myeloid neoplasms.

Biorbyt has a highly validated and comprehensive range of CD3 proteins, antibodies and genes including the difficult to source Biotinylated Human CD3 epsilon and Human CD3E & CD3D heterodimer protein.  We also offer the hard to find Mouse CD3 epsilon protein.

Why not look through and refine your search for our whole CD3 range.

MAb to CD3

Catalog # Antibody Target, Reactivity and Applications
orb95026 CD3 Mouse Mab - clone 4A12-F6 - Reacts with Human - ELISA, WB, IHC-P, IP
orb69238 CD3 Mouse Mab - Clone 4B10 - Reacts with Human - ELISA, WB, IHC-P, IF/ICC, FACS
orb89440 CD3 Mouse Mab - Reacts with Human - ELISA, WB, IHC-P, IF/ICC
orb69252 CD3E Mouse Mab - Clone 4E2 - Reacts with Human - ELISA, WB, IHC-P, IF/ICC, FACS
orb323391 CD3 Mouse Mab - Clone PC3/188A - Reacts with Rt, Rb, Ck, GP, Mk, Hrs, Pig - WB, IHC-P
orb314892 CD3 Epsilon Hamster Mab - Clone 145-2C11 - Reacts with Mouse - WB, IP, FACS
orb314895 CD3 Epsilon Mouse Mab - Clone UCHT1 - Reacts with Human - WB, IHC-P, FACS

PAb to CD3

Catalog #Antibody Target, Reactivity and Applications
orb348965 CD3 Rabbit Pab - Reacts with Hu, Ms, Rt - WB, IHC-P
orb378644 CD3 Epsilon Rabbit Pab - Reacts with Hu, Ms - WB, IHC-P, IF/ICC, FACS
orb10313 CD3 Rabbit Pab - Reacts with Hu, Ms, Rt - ELISA, WB, IHC-P, IHC-Fr, IF/ICC, IP
orb1175 CD3 Epsilon Rabbit Pab - Reacts with Mouse, Rat - WB, IHC-P, FACS, P-ELISA
orb33194 CD3 Rabbit Pab - Reacts with Hu - ELISA, WB, IHC-P, FACS
orb135199 CD3E Rabbit Pab - Reacts with Hu, Ms, Rt - WB, IHC-P, IF/ICC
orb248225 CD3 Rabbit Pab - Reacts with multiple species - WB, IP, FACS

CD3 Proteins

Catalog #Protein
orb195239 Mouse Human CD3body (Biotin)
orb348808 Mouse CD3 epsilon Protein, FcTag
orb393350 Human CD3 epsilon & CD3 delta Heterodimer
orb348813 Human CD3 epsilon & CD3 gamma Heterodimer protein
orb257323 Monkey CD3 epsilon protein
orb257326 Human CD3 epsilon protein