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CD3 Reagents
CD3: Cluster of differentiation 3
This T-cell receptor helps to activate both cytotoxic T-cells (CD8+ naive T-cells) and T helper cells (CD4+ naive T-cells). Present as a protein complex, it comprises 4 distinct chains. In mammals, this complex contains a gamma, delta and two epsilon chains.
The CD3γ, CD3δ and CD3ε chains are highly related cell-surface proteins and contain a single extracellular immunoglobulin domain.
CD3 antigen can be found bound to the membranes of all mature T-cells and in virtually no other cell type. This high specificity, combined with its presence at all stages of T-cell development makes it a useful T-cell marker for IHC tissue sections. The antigen is also present in almost all T-cell lymphomas and leukaemias, allowing their differentiation from similar B-cell and myeloid neoplasms.
Biorbyt has a highly validated and comprehensive range of CD3 proteins, antibodies and genes including the difficult to source Biotinylated Human CD3 epsilon and Human CD3E & CD3D heterodimer protein. We also offer the hard to find Mouse CD3 epsilon protein.
Why not look through and refine your search for our whole CD3 range.
MAb to CD3
| Catalog # | Antibody Target, Reactivity and Applications |
|---|---|
| orb95026 | CD3 Mouse Mab - clone 4A12-F6 - Reacts with Human - ELISA, WB, IHC-P, IP |
| orb69238 | CD3 Mouse Mab - Clone 4B10 - Reacts with Human - ELISA, WB, IHC-P, IF/ICC, FACS |
| orb89440 | CD3 Mouse Mab - Reacts with Human - ELISA, WB, IHC-P, IF/ICC |
| orb69252 | CD3E Mouse Mab - Clone 4E2 - Reacts with Human - ELISA, WB, IHC-P, IF/ICC, FACS |
| orb323391 | CD3 Mouse Mab - Clone PC3/188A - Reacts with Rt, Rb, Ck, GP, Mk, Hrs, Pig - WB, IHC-P |
| orb314892 | CD3 Epsilon Hamster Mab - Clone 145-2C11 - Reacts with Mouse - WB, IP, FACS |
| orb314895 | CD3 Epsilon Mouse Mab - Clone UCHT1 - Reacts with Human - WB, IHC-P, FACS |
PAb to CD3
| Catalog # | Antibody Target, Reactivity and Applications |
|---|---|
| orb348965 | CD3 Rabbit Pab - Reacts with Hu, Ms, Rt - WB, IHC-P |
| orb378644 | CD3 Epsilon Rabbit Pab - Reacts with Hu, Ms - WB, IHC-P, IF/ICC, FACS |
| orb10313 | CD3 Rabbit Pab - Reacts with Hu, Ms, Rt - ELISA, WB, IHC-P, IHC-Fr, IF/ICC, IP |
| orb1175 | CD3 Epsilon Rabbit Pab - Reacts with Mouse, Rat - WB, IHC-P, FACS, P-ELISA |
| orb33194 | CD3 Rabbit Pab - Reacts with Hu - ELISA, WB, IHC-P, FACS |
| orb135199 | CD3E Rabbit Pab - Reacts with Hu, Ms, Rt - WB, IHC-P, IF/ICC |
| orb248225 | CD3 Rabbit Pab - Reacts with multiple species - WB, IP, FACS |