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Catalog Number | orb44713 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal to CD163. CD163, also known as M130, is a member of the scavenger receptor family, accounting for the clearance of hemoglobin-haptoglobin complexes during limited hemolysis, which protects the body, in particular the kidneys, against heme-mediated oxidative damages. It does not have measurable affinity for noncomplexed hemoglobin or haptoglobin. Immunomodulatory role of CD163 has been postulated. CD163 is expressed by cells of the monocyte-macrophage lineage and its extracellular part also circulates in plasma as a soluble protein, especially during sepsis and other conditions affecting macrophage activity, when its level may raise manyfold. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | GHI/61 |
Tested applications | FC, IHC-Fr, IP, WB |
Reactivity | Human |
Isotype | Mouse IgG1 kappa |
Immunogen | Hairy cell leukemia cells |
Concentration | 1 mg/ml |
Dilution range | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
Purity | Purified by protein-A affinity chromatography. |
Conjugation | Unconjugated |
Target | CD163 |
Entrez | 9332 |
UniProt ID | Q86VB7 |
Storage | Store at 2-8°C. Do not freeze. |
Buffer/Preservatives | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Alternative names | anti-Cluster Of Differentiation antibody, anti-CD Read more... |
Note | For research use only |
Application notes | Flow cytometry: Recommended dilution: 1-4 μg/ml. |
Expiration Date | 12 months from date of receipt. |
Immunohistochemical analysis of paraffin embedded and formalin fixed human liver tissue using CD163 antibody
Flow cytometric analysis of normal human peripheral blood cells using CD163 antibody
IHC-P of Human spleen tissue using CD163 antibody
IHC-P of human placenta tissue using CD163 antibody
ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB | |
Canine, Equine, Porcine, Rat | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
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