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Product Overview
Product Name c-FOS antibody
Catalog Number orb10375
Species/HostRabbit
ReactivityHuman, Mouse, Rat
Predicted Reactivity Porcine
ConjugationUnconjugated
Tested applicationsELISA, ICC, IF, IHC-P, WB
Immunogen KLH conjugated synthetic peptide derived from human c-fos:1-100/380
Target c-Fos
Alternative Names
Product Properties
Form/Appearance Liquid: 0.01M TBS (pH7.4), 0.5% BSA, 0.015% ProClin™ 300 and 25% glycerol
Concentration - 5 μg (in 100 μl): 0.05 mg/ml
- 20 μg (in 100 μl): 0.2 mg/ml
- 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity Affinity purified by Protein A
MW 41 kDa
Uniprot ID P01100 (Human); P01101 (Mouse); P12841 (Rat)
NCBI NP_005243.11; NM_005252.31
Entrez 2353
Product Description

Rabbit polyclonal antibody to c-Fos which is also known as cellular oncogene fos whose expression can be detected in the quiescent cells but it is significantly expressive in stimulated cells. It is found in the nucleus. It can perform functions like positive regulation of pri-miRNA transcription from RNA polymerase II promoter and transcription factor binding. It plays a role in signal transduction, cell proliferation and differentiation. In growing cells, it activates phospholipid synthesis, possibly by activating CDS 1 and PI4K2A.

Application Notes
Dilution Range WB: 1:500-2000, ELISA: 1:500-1000, IHC-P: 1:400-800, ICC: 1:100-500, IF: 1:100-500
Validation Images
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using c-Fos antibody
Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using c-Fos antibody
IHC-P of rat spinal cord tissue using c-Fos antibody
IHC-P of rat spinal cord tissue using c-Fos antibody
Immunohistochemical analysis of formalin fixed and paraffin embedded rat brain tissue using c-Fos antibody
Immunohistochemical analysis of formalin fixed and paraffin embedded rat brain tissue using c-Fos antibody
IHC-P of human gastric carcinoma (c-Fos antibody at 1:200)
IHC-P of human gastric carcinoma (c-Fos antibody at 1:200)
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