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BDNF Protein, Human/Murine/Rat, Recombinant

BDNF Protein, Human/Murine/Rat, Recombinant

Catalog Number: orb1962089

DispatchUsually dispatched within 5-10 working days
$ 260.00
Catalog Numberorb1962089
CategoryProteins
DescriptionBrain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
TagTag Free
Purity> 99.9%
MW14 KDa (reducing condition)
UniProt IDP23560
Protein SequenceHis129-Arg247
Expression SystemE. coli
Biological OriginHuman,Mouse,Rat
Biological ActivityBrain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
Expression RegionHis129-Arg247
Storage-20°C
NoteFor research use only
Application notesReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Expiration Date6 months from date of receipt.
  • Human/Murine/Rat BDNF Protein [orb1471779]

    Greater than 95% as determined by reducing SDS-PAGE.

    13 KDa

    Mammalian

    10 μg, 50 μg