| Catalog Number | orb60991 |
|---|---|
| CAS Number | 319460-85-0 |
| Application notes | AXB |
| Note | For research use only. |
| Expiration Date | 12 months from date of receipt. |
| Description | Axitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively. Axitinib is currently in Phase III clinical trial in advanced hepatocellular carcinoma. Axitinib is superior as second-line therapy compared with sorafenib, the current standard of care. |
Axitinib Chemical Structure
Chemical structure of Axitinib, Free Base
