Axitinib, Free Base

Catalog Number: orb60991

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Catalog Numberorb60991
CAS Number319460-85-0
Application notesAXB
NoteFor research use only.
Expiration Date12 months from date of receipt.
DescriptionAxitinib (AG-013736) is a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM, respectively. Axitinib is currently in Phase III clinical trial in advanced hepatocellular carcinoma. Axitinib is superior as second-line therapy compared with sorafenib, the current standard of care.
Axitinib Chemical Structure
Axitinib Chemical Structure
Chemical structure of Axitinib, Free Base
Chemical structure of Axitinib, Free Base