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AREG Protein, Human, Recombinant
Catalog Number: orb1961448
| Catalog Number | orb1961448 |
|---|---|
| Category | Proteins |
| Description | Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy. |
| Tag | Tag Free |
| Purity | 98.00% |
| MW | 16 KDa (reducing condition) |
| UniProt ID | P15514 |
| Protein Sequence | Ser101-Lys198 |
| Expression System | E. coli |
| Biological Origin | Human |
| Biological Activity | Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. AREG may also play a protective role in Bleomycin-Induced Pneumopathy. |
| Expression Region | Ser101-Lys198 |
| Storage | -20°C |
| Note | For research use only |
| Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Expiration Date | 6 months from date of receipt. |
- Item 1 of 1
Human AREG protein (Active) [orb359172]
> 95% as determined by SDS-PAGE and HPLC.
11.3 kDa
E.Coli
10 μg, 100 μg, 500 μg - Item 1 of 1
- Item 1 of 1
Human AREG Protein, hFc Tag [orb1290823]
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 44.9 kDa after removal of the signal peptide. The apparent molecular mass of AREG-hFc is approximately 53-70 kDa due to glycosylation.
Mammalian
100 μg, 10 μg, 50 μg Human AREG protein [orb391254]
ELISA, MS, SDS-PAGE, WB
Greater than 95% as determined by reducing SDS-PAGE.
E. coli
500 μg, 50 μg, 10 μgRecombinant Human Amphiregulin protein(AREG) (Active) [orb1650838]
100 μg, 50 μg, 250 μg, 500 μg, 1 mg, 10 μg
