Anti-TSLP Reference Antibody (tezepelumab)

• Catalog Number: orb1818223
• Category: Antibodies
• Description: Recombinant Antibody
• Clonality: Monoclonal
• Tested applications: ELISA, FC
• Reactivity: Human, Monkey
• Isotype: IgG2
• Antibody Type: Primary Antibody
• Concentration: 1mg/ml
• Form/Appearance: Purified monoclonal antibody supplied in PBS, pH 6.0, without preservative.This antibody is purified through a protein A column.
• Conjugation: Unconjugated
• MW: 144.6
• UniProt ID: Q969D9
• Protein Sequence: TSLP
• Expression System: CHO Cell
• Endotoxins: < 0.001EU/μg,determined by LAL method.
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
• Alternative names: Thymic stromal lymphopoietin, TSLP
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

The purity of Anti-TSLP Reference Antibody (tezepelumab) is more than 98.64%, determined by SEC-HPLC.

Immobilized human TSLP His at 2 µg/mL can bind Anti-TSLP Reference Antibody (tezepelumab), EC50=0.0518 µg/mL

Tezepelumab reduced levels of IL13 in BALF of OVA asthma model on B-hTSLP/hTSLPR mice. The result showed significant IL13 inhibition effects at 15 mpk.

Anti-TSLP Reference Antibody (tezepelumab) -induced FACS Blocking activity was evaluated using TSLPR/IL7R-CHO-K. The IC50 was approximately 0.0802 µg/mL.

Anti-TSLP Reference Antibody (tezepelumab) on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%