Amyloid Oligomers (A11) antibody

• Catalog Number: orb152846
• Category: Antibodies
• Description: Rabbit polyclonal to Amyloid Oligomers (ATTO-594). Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid- beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimers symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinsons disease, and accumulation of polyglutamine-containing aggregates in Huntingtons disease.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, ICC, IHC, IP, WB
• Reactivity: Human, Mouse, Other, Rat
• Immunogen: Synthetic molecular mimic of soluble oligomers
• Dilution range: The suggested dilution for the current lot of SPC-506 in Western Blot and Dot Blot is 1:100
• Conjugation: ATTO-594
• Target: Amyloid Oligomers (A11)
• Entrez: 8666
• UniProt ID: P05067
• NCBI: NM_000484.2
• Storage: Conjugated antibodies should be stored at 4°C
• Buffer/Preservatives: PBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
• Alternative names: Amyloid Oligomer alpha beta antibody, A11 antibody
• Note: For research use only
• Application notes: A 1:200 dilution of SPC-506 was sufficient for detection of amyloid oligomers in 10 µg of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
• Expiration Date: 12 months from date of receipt.