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Amyloid Oligomers (A11) antibody

Amyloid Oligomers (A11) antibody

Catalog Number: orb152843

DispatchUsually dispatched within 2-3 weeks
$ 558.00
Catalog Numberorb152843
CategoryAntibodies
DescriptionRabbit polyclonal to Amyloid Oligomers (ATTO-390). Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. Many degenerative diseases are known to be related to the accumulation of misfolded proteins as amyloid fibres. These include the amyloid- beta peptide plaques and tau neurofibrillary tangles in senile plaques of Alzheimers symptomology, the deposition of alpha-synuclein in the Lewy bodies of Parkinsons disease, and accumulation of polyglutamine-containing aggregates in Huntingtons disease.
Species/HostRabbit
ClonalityPolyclonal
Tested applicationsELISA, ICC, IHC, IP, WB
ReactivityHuman, Mouse, Other, Rat
ImmunogenSynthetic molecular mimic of soluble oligomers
Dilution rangeThe suggested dilution for the current lot of SPC-506 in Western Blot and Dot Blot is 1:100
ConjugationATTO-390
TargetAmyloid Oligomers (A11)
Entrez8666
UniProt IDP05067
NCBINM_000484.2
StorageConjugated antibodies should be stored at 4°C
Buffer/PreservativesPBS, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated
Alternative namesAmyloid Oligomer alpha beta antibody, A11 antibody
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NoteFor research use only
Application notesA 1:200 dilution of SPC-506 was sufficient for detection of amyloid oligomers in 10 µg of mouse brain lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.
Expiration Date12 months from date of receipt.
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