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ACE-083

ACE-083

Catalog Number: orb2815005

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Catalog Numberorb2815005
CategorySmall Molecules
DescriptionACE-083 is a follistatin-based therapeutic agent known for its localized mechanism of action. It works by binding to myostatin and other muscle-regulating factors to enhance muscle mass. ACE-083 has undergone testing in various clinical trials for different neuromuscular diseases, yielding mixed results. Notably, in a Phase 2 clinical trial for FSHD, it increased muscle volume, but did not improve function, leading to the discontinuation of its use for FSHD treatment.
CAS Number81080-10-6
MW345.48
SMILESO=C(NC=1C=C(C(O)=C(C1)CN2CCCCC2)CN3CCCCC3)C
FormulaC20H31N3O2
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • Efmitermant alfa [orb1942266]

    Unconjugated

    5 mg, 1 mg
  • ACE-083 [orb1785947]

    [81080-10-6]

    345.479

    C20H31N3O2

    250 mg, 1 g, 100 mg