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AA-T3A-C12
Catalog Number: orb1818882
| Catalog Number | orb1818882 |
|---|---|
| Category | Small Molecules |
| Description | AA-T3A-C12 is an anisamide ligand-tethered lipidoid (AA-lipidoid) with high potency and selectivity to deliver RNA payloads to activated fibroblasts. HSP47 siRNA (siHSP47)-loaded AA-T3A-C12 LNP achieves ~65% knockdown and dramatically reduces liver fibrosis, which significantly outperforms the benchmark DLin-MC3-DMA (MC3) LNP. |
| CAS Number | [2938207-23-7] |
| MW | 1059.72 |
| SMILES | OC(CCCCCCCCCC)CN(CC(O)CCCCCCCCCC)CCCN(CCCNC(C1=CC=C(OC)C=C1)=O)CCCN(CC(O)CCCCCCCCCC)CC(O)CCCCCCCCCC |
| Formula | C65H126N4O6 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
