8-Oxo-dGTP

SKU: orb64224

Description

8-Hydroxy-dGTP

Images & Validation

• Application Notes:
  Influence on base excision repair; Influence on erroneous incorporation by DNA-polymerases; Hydrolysis to 8-oxo-dGMP by E.-coli MutT; Triggering cell senescence through formation of ROS. ; Spectroscopic Propertie: λmax 245 nm, ε 12.3 L mmol-1 cm-1 (Tris-HCl, pH 7.5).

Key Properties

• CAS Number: 139307-94-1
• MW: Theoretical MW: 523.18 g/mol (free acid); Detected MW: 522.99 g/mol (free acid)
• Purity: ≥ 95% (HPLC)
• Formula: C₁₀H₁₆N₅O₁₄P₃
• SMILES: Nc1[nH]c(=O)c2c(n(c(=O)[nH]2)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)C2)n1

Storage & Handling

• Storage: store at -20 °C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

8-Hydroxy-dGTP, 8-Oxo-2'-deoxyguanosine-5'-triphosphate, Sodium salt

Chemical structure of 8-Oxo-dGTP

Chemical structure of 8-Oxo-dGTP

Compound Identifiers

PubChem CID

135398565

Xiangxiang Wang, Yuyu Zhao, Zhaohua Hou, Xiaoxu Chen, Shuangying Jiang, Wei Liu, Xin Hu, Junbiao Dai, Guangh Large-scale pathway reconstruction and colorimetric screening accelerate cellular metabolism engineering Metabolic Engineering, 80, 107-118 (2023)

PubMed: 37717647