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Catalog Number | orb64224 |
---|---|
Category | Tools |
Description | 8-Hydroxy-dGTP |
CAS Number | 139307-94-1 |
Concentration | 10 mM-11 mM |
Form/Appearance | solution in water; Color: colorless to slightly yellow; pH: 7.5 ± 0.5 |
Purity | ≥ 95% (HPLC) |
MW | Theoretical MW: 523.18 g/mol (free acid); Detected MW: 522.99 g/mol (free acid) |
SMILES | Nc1[nH]c(=O)c2c(n(c(=O)[nH]2)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)C2)n1 |
Formula | C10H16N5O14P3 |
Storage | store at -20 °C |
Note | For research use only |
Application notes | Influence on base excision repair; Influence on erroneous incorporation by DNA-polymerases; Hydrolysis to 8-oxo-dGMP by E.-coli MutT; Triggering cell senescence through formation of ROS. < br>< b>Spectroscopic Propertie: λmax 245 nm, ε 12.3 L mmol-1 cm-1 (Tris-HCl, pH 7.5). |
Expiration Date | 12 months from date of receipt. |
Xiangxiang Wang, Yuyu Zhao, Zhaohua Hou, Xiaoxu Chen, Shuangying Jiang, Wei Liu, Xin Hu, Junbiao Dai, Guangh Large-scale pathway reconstruction and colorimetric screening accelerate cellular metabolism engineering Metabolic Engineering, 80, 107-118 (2023)
Chemical structure of 8-Oxo-dGTP
Chemical structure of 8-Oxo-dGTP
FC, IHC-P, WB | |
Human, Mouse | |
Rabbit | |
Polyclonal | |
Unconjugated |
IH, WB | |
Human, Mouse, Rat | |
Rabbit | |
Polyclonal | |
Unconjugated |
FC, ICC, IHC, IP, WB | |
Human | |
Rabbit | |
Recombinant | |
Unconjugated |
Greater than 90% as determined by SDS-PAGE. | |
16.9 kDa | |
Yeast |