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HPV16 E6 protein antibody

Datasheet
Size Price Availability Qty
5 μg (Trial size)
$60
Available now for quick dispatch
20 μg (Trial size)
$128
Available now for quick dispatch
100 μg
$366
Usually dispatched within 5-10 working days
200 μg
$595
Usually dispatched within 5-10 working days
1 mg
$1,063
Usually dispatched within 5-10 working days
Shipping charges : Freight/Packing: $34

Rabbit polyclonal antibody to HPV16-E6/E6 and is also known as protein E6 whose expression can be detected in the early protein. It is found in the host cytoplasm. This protein plays a major role with other cellular targets including BAK1, Fas-associated death domain-containing protein (FADD) and procaspase 8, are degraded by E6/E6AP causing inhibition of apoptosis and in the induction and maintenance of cellular transformation. The complex E6/E6AP targets several other substrates to degradation via the proteasome including host DLG1 or NFX1, a repressor of human telomerase reverse transcriptase (hTERT).

Product Information

PubMed 25500889; 25565864
Category Primary antibodies
Product name HPV16 E6 protein
Catalog Number orb10837
Host Rabbit
Clonality Polyclonal
Tested applications IHC-P, IF/ICC, P-ELISA
Dilution range P-ELISA: 1:500-1000, IHC-P: 1:400-800, IF/ICC: 1:100-500
Concentration - 5 μg (in 100 μl): 0.05 mg/ml
- 20 μg (in 100 μl): 0.2 mg/ml
- 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Reacts with Human
NCBI NP_041325.11; NC_001526.21
Conjugation Unconjugated
Immunogen KLH conjugated synthetic peptide derived between 95-148 amino acids of human HPV16-E6/E6
Purity Affinity purified by Protein A
MW 11 kDa
Isotype IgG
Form Liquid: 0.01M TBS (pH7.4), 0.5% BSA, 0.015% ProClin™ 300 and 25% glycerol
References 1. TALEN-mediated targeting of HPV oncogenes ameliorates HPV-related cervical malignancy.
2.Disruption of human papillomavirus 16 E6 gene by clustered regularly interspaced short palindromic repeat/Cas system in human cervical cancer cells.
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Target HPV16 E6
Alternative names
anti-E6 antibody, anti-HPV16-E6/E6 antibody, anti-Human Papilloma Virus antibody, anti-Human papillomavirus type 16 E6 antibody, anti-Human papillomavirus type 18 E6 antibody, anti-Protein E6 antibody

HPV16 E6 protein antibody Documents

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Click image to enlarge
Immunohistochemical analysis of formalin fixed and paraffin embedded human cervical carcinoma using HPV16 E6 protein antibody
 
 
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